Sodium Danshensu (Danshensu Sodium), the sodium salt of danshensu, is a novel, potent, naturally occuring phenolic acid of caffeic acid derivatives isolated from Salvia miltiorrhiza with various biological activity (e.g, antioxidant, anti-inflammatory).
Abiraterone (formerly also known as CB 7598; CB7598; CB-7598; trade name Zytiga) is a novel, higly potent, irreversible and selective CYP17 inhibitor with potential antineoplastic activity.
Ketoconazole (Ketoconazol; Fungoral, Nizoral, Kuric, Xolegel, Ketoderm; Extina; R-41400; R 41400), a CYP3A4 and 24A1 inhibitor and antifungal agent, is a potent and synthetic imidazole-based antifungal drug used primarily to treat fungal infections.
Benzbromarone (L2214; L 2214; MJ-10061; MJ10061; L-2214; L2214-Labaz; Narcaricin; Normurat), an approved anti-gout drug (uricosuric drug) for the last 30 years, is a potent CYP2C9 inhibitor with Ki value of 19.3 nM.
Abiraterone Acetate (brand name Zytiga; formerly CB-7598; CB7598; CB 7598), the 3-acetylated and prodrug form of Abiraterone, is an irreversible and steroidal cytochrome CYP17 inhibitor with potential antitumor activity.
Dazoxiben HCl is a potent and orally bioactive antithrombotic agent acting as a thromboxane (TX) synthase inhibitor.
Itraconazole (Orungal, Oriconazole, Sporanox, R51211; R-51211), a marketed triazole-based antifungal drug since 1984, is a potent inhibitor of CYP3A4 that has been widely used for the treatment of fungal infections.
Stiripentol (formerly known as BCX-2600; BCX2600; STP; trade name: Diacomit) is an FDA-approved anticonvulsant drug that inhibits the activity of several cytochromes P450 (P450s).
Pioglitazone HCl (also known as Actos; U-72107A; AD-4833; AD4833, U-72107E), the hydrochloride salt of Pioglitazone which is approved and thiazolidinedione-based anti-diabetic drug, is a selective PPARϒ agonist with hypoglycemic activity.
Voriconazole (UK-109496; UK109496; trade name Vfend) is a 2nd-generation and potent triazole-based antifungal drug used for treating a variety of fungal infections.