Voriconazole
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
Size | Price | Stock |
---|---|---|
2g | $650 | Check With Us |
5g | $1050 | Check With Us |
10g | $1575 | Check With Us |
Cat #: V0802 CAS #: 137234-62-9 Purity ≥ 98%
Description: Voriconazole (UK-109496; UK109496; trade name Vfend) is a 2nd-generation and potent triazole-based antifungal drug used for treating a variety of fungal infections.
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Molecular Weight (MW) | 349.31 |
---|---|
Molecular Formula | C16H14F3N5O |
CAS No. | 137234-62-9 |
Storage | -20℃ for 3 years in powder formr |
-80℃ for 2 years in solvent | |
Solubility In Vitro | DMSO: 70 mg/mL (200.4 mM)r |
Water: <1 mg/mLr | |
Ethanol: 20 mg/mL (57.3 mM) | |
Solubility In Vivo | 30% PEG400+0.5% Tween80+5% propylene glycol: 10mg/mL |
SMILES Code | C[C@@H](C1=NC=NC=C1F)[C@@](O)(C2=CC=C(F)C=C2F)CN3N=CN=C3 |
Synonyms | UK-109496; UK 109496; Voriconazole; UK109496; UK109,496; UK-109,496; UK 109,496; Vfend |
Solvent volume to be added | Mass (the weight of a compound) | |||
---|---|---|---|---|
Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
1mM | 2.8628 mL | 14.3139 mL | 28.6279 mL | 57.2557 mL |
5mM | 0.5726 mL | 2.8628 mL | 5.7256 mL | 11.4511 mL |
10mM | 0.2863 mL | 1.4314 mL | 2.8628 mL | 5.7256 mL |
20mM | 0.1431 mL | 0.7157 mL | 1.4314 mL | 2.8628 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.