Voriconazole

This product is for research use only, not for human use. We do not sell to patients.

Voriconazole
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
2g$650Check With Us
5g$1050Check With Us
10g$1575Check With Us

Cat #: V0802 CAS #: 137234-62-9 Purity ≥ 98%

Description: Voriconazole (UK-109496; UK109496; trade name Vfend) is a 2nd-generation and potent triazole-based antifungal drug used for treating a variety of fungal infections.

References: Nickie D Greer. Voriconazole: the newest triazole antifungal agent.Proc (Bayl Univ Med Cent). 2003 Apr;16(2):241-8.

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Product Promise

Promise
Molecular Weight (MW)349.31
Molecular FormulaC16H14F3N5O
CAS No.137234-62-9
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 70 mg/mL (200.4 mM)r
Water: <1 mg/mLr
Ethanol: 20 mg/mL (57.3 mM)
Solubility In Vivo30% PEG400+0.5% Tween80+5% propylene glycol: 10mg/mL
SMILES CodeC[C@@H](C1=NC=NC=C1F)[C@@](O)(C2=CC=C(F)C=C2F)CN3N=CN=C3
SynonymsUK-109496; UK 109496; Voriconazole; UK109496; UK109,496; UK-109,496; UK 109,496; Vfend
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM2.8628 mL14.3139 mL28.6279 mL57.2557 mL
5mM0.5726 mL2.8628 mL5.7256 mL11.4511 mL
10mM0.2863 mL1.4314 mL2.8628 mL5.7256 mL
20mM0.1431 mL0.7157 mL1.4314 mL2.8628 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.