Benzbromarone

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
2g	$160	Check With Us
5g	$280	Check With Us
10g	$420	Check With Us

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Cat #: V0813 CAS #: 3562-84-3 Purity ≥ 99%

Description: Benzbromarone (L2214; L 2214; MJ-10061; MJ10061; L-2214; L2214-Labaz; Narcaricin; Normurat), an approved anti-gout drug (uricosuric drug) for the last 30 years, is a potent CYP2C9 inhibitor with Ki value of 19.3 nM.

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Physicochemical and Storage Information
Protocol
Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	424.08
Molecular Formula	C17H12Br2O3
CAS No.	3562-84-3
Storage	-20℃ for 3 years in powder formr
Storage	-80℃ for 2 years in solvent
Solubility In Vitro	DMSO: 85 mg/mL (200.4 mM)r
	Water: <1 mg/mLr
	Ethanol: 9 mg/mL (21.2 mM)
SMILES Code	O=C(C1=CC(Br)=C(O)C(Br)=C1)C2=C(CC)OC3=CC=CC=C23
Synonyms	L2214; MJ10061; L 2214; MJ-10061; L-2214; L2214-Labaz; Narcaricin; Normurat; Benzbromarone; MJ 10061;

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	2.3580 mL	11.7902 mL	23.5805 mL	47.1609 mL
5mM	0.4716 mL	2.3580 mL	4.7161 mL	9.4322 mL
10mM	0.2358 mL	1.1790 mL	2.3580 mL	4.7161 mL
20mM	0.1179 mL	0.5895 mL	1.1790 mL	2.3580 mL

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.