Banoxantrone 2HCl (AQ4N), the dihydrochloride salt of Banoxantrone, is a hypoxia-activated and bioreductive prodrug that can be reduced under hypoxia (e.g. in hypoxic cells) to a stable, compound AQ4, which is a potent topoisomerase II inhibitor with antitumor activity.

Gatifloxacin (formerly also known as AM-1155, CG5501, BMS-206584; PD135432; Tequin; Zymar; Gatiflo; Zymaxid; AM 1155) is a fourth-generation antibiotic of the fluoroquinolone family used to treat tuberculosis and pneumonia, it inhibits the bacterial enzymes DNA gyrase and topoisomerase IV.

Levofloxacin [(-)-Ofloxacin, Levaquin, Tavanic, Fluoroquinolone, Iquix, Quixin], a synthetic fluoroquinolone and the levo isomer of ofloxacin, is a broad-spectrum antibacterial drug approved for treating UTIs, RTIs etc.

Etoposide (formerly VP-16, VP-16213; Toposar; VePesid; Lastet; EPEG), a chemotherapeutic drug used for the treatments of various cancers, is a semisynthetic derivative of the naturally occuring podophyllotoxin which inhibits DNA synthesis via topoisomerase II inhibitory activity.

Enoxacin (formerly AT-2266; CI-919; NSC-629661; Penetrex; Comprecin; Enoxacino) is an orally bioavailable and broad-spectrum fluoroquinolone antibiotic used to treat various infections, such as UTIs-urinary tract infections and gonorrhea.

Moxifloxacin HCl (formerly BAY12-8039; BAY12-8039; BAY 12-8039; Avelox, Avalox, Avelon, Vigamox, Moxeza),the hydrochloride salt of moxifloxacin, is an orally bioactive, broad spectrum and 4th generation antibacterial drug of the fluoroquinolone class with high activity against both Gram positive and Gram negative bacteria.

Marbofloxacin (Forcyl, Kelacyl, Zeniquin, Aristos, Boflox, Marbocyl, Aurizon), a carboxylic acid derivative, is a 3rd generation and broad spectrum antibiotic of the fluoroquinolone class used as a veterinary medication.

Clinafloxacin HCl (also known as CI-960, PD127391, AM-1091), the hydrochloride salt of Clinafloxacin, is an investigational, broad-spectrum fluoroquinolone class of antibiotic that inhibits both DNA gyrase and topoisomerase IV dually in Streptococcus pneumonia.

Flumequine (formerly R-802; R 802; R802) is a synthetic quinolone, 1st generation and broad-spectrum chemotherapeutic antibiotic that was once used to treat bacterial infections but has been removed from market.

Teniposide (VM-26; HSDB-6546; NSC-122819; CCRIS-2058; Vumon; Vehem; EPT; PTG) is a semisynthetic podophyllotoxin derivative and chemotherapeutic agent mainly used in the treatment of childhood acute lymphocytic leukemia (ALL).