Voreloxin HCl (formerly known as AG-7352; SNS-595; SPC 595; AG 7352; SNS595, AG-7352; Vosaroxin), the hydrochloride salt of Voreloxin which is a naphthyridine analog, is a novel and potent Topoisomerase II inhibitor with a broad-spectrum antineoplastic activity.

Daunorubicin (also know as Daunomycin; RP 13057; Rubidomycin), an anthracycline analogue and a topoisomerase II inhibitor is mainly used as an antibiotic.

Mitoxantrone HCl (formerly NSC-301739; NSC301739; DHAQ; CL-232325; Mitroxone; Neotalem; Onkotrone; Pralifan; Novantrone), the hydrochloride salt of Mitoxantrone which is an anthracenedione anticancer agent, is a potent type II topoisomerase inhibitor with potential antitumor activity.

PluriSIn #2 is a novel,potent and selective topoisomerase II α (TOP2A) transcriptional inhibitor .

Daunorubicin HCl (Daunomycin; RP-13057; Rubidomycin; Ondena; Rubilem; DNM; DNR; DRB; FI6339; RP13057), the hydrochloride salt of daunorubicin, is an anthracycline analog and a topoisomerase II inhibitor which is approved for use as an antibiotic and chemotherapeutic drug.

Pefloxacin mesylate dihydrate (Peflacine; 1589-RB; 1589RB; UNII-CX28QC6FU0; Peflacin; Pefloxacinium), the mesylate salt and dihydrated form of pefloxacin, is a broad-spectrum and 3rd generation fluoroquinolone antibiotic approved for treating bacterial infections.

Irinotecan (also known as CPT-11; Camptosar; Irinophore C; CPT11; Irinotecan lactone; Irinotecanum), a semisynthetic analog of camptothecin and the prodrug of 7-ethyl-10-hydroxy-camptothecin (SN-38), is a topoisomerase I inhibitor approved for use as an anticancer drug.

TAS-103 (also known as BMS-247615) is a potent and dual inhibitor of DNA topoisomerase I/II.

Ofloxacin (Hoe-280; DL8280; DL-8280, DR-3355, Hoe280, ORF-28489, Ru-43280) is a synthetic, orally bioavailable and broad-spectrum antibiotic of the fluorinated quinolone class used for the treatment of a variety of bacterial infections such as pneumonia, cellulitis, UTIs-urinary tract infections, prostatitis, and plague.

Dexrazoxane xHCl (formerly also known as ICRF-187, ADR-529) acts as an intracellular iron chelator, which decreases the formation of superoxide radicals, and is mainly used as a cardioprotective agent.