Levofloxacin [(-)-Ofloxacin]
This product is for research use only, not for human use. We do not sell to patients.
![Levofloxacin [(-)-Ofloxacin]](https://invivochem.net/wp-content/uploads/2023/05/CgAGS11tDWqAP2p7AAA44Y-vWeQ854.png "Levofloxacin [(-)-Ofloxacin]")
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 50g | $450 | Check With Us |
| 100g | $650 | Check With Us |
| 200g | $975 | Check With Us |
: Cat #: V1411 CAS #: 100986-85-4 Purity ≥ 98%
Description: Levofloxacin [(-)-Ofloxacin, Levaquin, Tavanic, Fluoroquinolone, Iquix, Quixin], a synthetic fluoroquinolone and the levo isomer of ofloxacin, is a broad-spectrum antibacterial drug approved for treating UTIs, RTIs etc.
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- Physicochemical and Storage Information
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- Related Biological Data
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| Molecular Weight (MW) | 361.37 |
|---|---|
| Molecular Formula | C18H20FN3O4 |
| CAS No. | 100986-85-4 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 24 mg/mL (66.4 mM)r |
| Water: 11 mg/mL (30.4 mM)r | |
| Ethanol: 9 mg/mL (24.9 mM) | |
| Synonyms | (-)-Ofloxacin; Fluoroquinolone; Levofloxacin, Levaquin, Tavanic, Iquix, Quixin |
| Protocol | In Vivo | Levofloxacin (10.7 mg/kg； Intraperitoneal injection, once daily for 10 days or 3 weeks) Time-dependent induction of toxic effects in the liver and heart of albino mice |
|---|---|---|
| Animal model | Matured male Albino mice | |
| Dosages | 10.7 mg/kg | |
| Administration | Intraperitoneal injection; 10.7 mg/kg, once daily for 10 days or 3 weeks |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.7672 mL | 13.8362 mL | 27.6725 mL | 55.3449 mL |
| 5mM | 0.5534 mL | 2.7672 mL | 5.5345 mL | 11.0690 mL |
| 10mM | 0.2767 mL | 1.3836 mL | 2.7672 mL | 5.5345 mL |
| 20mM | 0.1384 mL | 0.6918 mL | 1.3836 mL | 2.7672 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.