A2764 diHCl is a novel and potent inhibitor of TRESK.
Mitiglinide Calcium (formerly KAD-1229; S-21403; KAD1229; S21403; Glufast), the calcium salt of Mitiglinide, is a potassiun channel blocker that has been approved as a blood glucose-lowering drug for the treatment of type 2 diabetes.
Dronedarone HCl (formerly SR-33589; D4689; W3083; D03914; S-7529; RL01735), the hydrochloride salt of dronedarone, is a non-iodinated amiodarone analog approved for the treatment for Atrial fibrillation (AF).
Psora-4 is a novel, potent and selective small-molecule inhibitor of voltage-gated potassium channels – Kv1.3 with EC50 of 3 nM.
Nateglinide (formerly A-4166; trade names: Fastic, Starlix), a meglitinide analog, is a potent and orally bioavailable antihyperglycemic medication used for treating type 2 diabetes [non-insulin-dependent diabetes mellitus (NIDDM)].
A2793 inhibited TWIK-related acid-sensitive K+ channel (TASK)-1 (100 µM, 53.4% ± 13, 5%, n = 5).
GSK369796 dihydrochloride is a novel, potent and effective antimalarial and inhibits hERG potassium ion channel repolarization with an IC50 of 7.5 μM.
Probenecid (Benemid; Probecid; Benecid; Benuryl; Probenecid Martec; Probalan) is an OAT (organic anion transport) inhibitor which has been used as a medication to increase uric acid excretion in the urine.
AM-92016 HCl, the hydrochloride salt of AM-92016 (an oxypropanolamine analog of sotalol), is a novel, potent and specific IK inhibitor.
Gliclazide (S-1702; trade names Diamicron among others), a sulfonylurea insulin secretagogue, is an approved medication for the treatment of type 2 diabetes.