A2793
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 250mg | $1100 | Check With Us |
| 500mg | $1550 | Check With Us |
| 1g | $2250 | Check With Us |
: Cat #: V2418 CAS #: 88349-90-0 Purity ≥ 99%
Description: A2793 inhibited TWIK-related acid-sensitive K+ channel (TASK)-1 (100 µM, 53.4% ± 13, 5%, n = 5).
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- Physicochemical and Storage Information
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- Related Biological Data
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| Molecular Weight (MW) | 265.69 |
|---|---|
| Molecular Formula | C13H12ClNO3 |
| CAS No. | 88349-90-0 |
| Protocol | In Vitro | A2793 (100 µM) inhibits the unstimulated channel by 43.0±8.9% (n=5) while after ionomycin activation the reduction of the TRESK current is 85.5±2.9% (n=5) |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 3.7638 mL | 18.8189 mL | 37.6378 mL | 75.2757 mL |
| 5mM | 0.7528 mL | 3.7638 mL | 7.5276 mL | 15.0551 mL |
| 10mM | 0.3764 mL | 1.8819 mL | 3.7638 mL | 7.5276 mL |
| 20mM | 0.1882 mL | 0.9409 mL | 1.8819 mL | 3.7638 mL |
The molarity calculator equation
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The dilution calculator equation
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This equation is commonly abbreviated as: C1 V1 = C2 V2
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Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.