H151 (H-151) is a potent, selective and irreversible STING antagonist/inhibitor with the potential to be used for autoimmune diseases such as arthritis and other inflammatory conditions.
C-178 is a covalent inhibitor of STING which binds to Cys91, blocking palmitoylation-induced clustering of STING.
STING inhbitor 1 is a novel and potent inhibitor of STING, which inhibits the activation of Sting signaling pathway.
SP-23 (SP23) is a novel, first-in-class and potent STING-targeting PROTAC degrader based on C-170 (STING inhibitor) with anti-inflammatory effects.
G10 (STING agonist-1) is a novel, potent human-specific STING agonist, triggering IRF3/IFN-associated transcription in human fibroblasts.
C-170 is a novel, potent and covalent STING (stimulator of interferon genes) inhibitor with potential anti-inflammatory activities.
C-171 is a novel and potent STING (stimulator of interferon genes) inhibitor.
cGAMP (also known as Cyclic GMP-AMP; 3′,3′-cGAMP) is a cyclic nucleotide acting as a STING agonist.
C-176 is a highly potent, covalent/irreversible and selective small-molecule antagonist/inhibitor of the stimulator of interferon genes (STING) protein, which is a central signalling component of the intracellular DNA sensing pathway.
MSA 2 (MSA2; MSA-2) is a novel, orally bioactive and potent non-nucleotide agonist of stimulator of interferon genes (STING) with potential antitumor activity.