C-170
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 500mg | $750 | Check With Us |
| 1g | $1250 | Check With Us |
| 5g | $3160 | Check With Us |
: Cat #: V2342 CAS #: 346691-38-1 Purity ≥ 99%
Description: C-170 is a novel, potent and covalent STING (stimulator of interferon genes) inhibitor with potential anti-inflammatory activities.
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| Molecular Weight (MW) | 288.30 |
|---|---|
| Molecular Formula | C15H16N2O4 |
| CAS No. | 346691-38-1 |
| SMILES Code | O=C(C1=CC=C([N+]([O-])=O)O1)NC2=CC=C(CCCC)C=C2 |
| Synonyms | C-170; STING inhibitor C-170 |
| Protocol | In Vitro | THP-1 cells are pretreated with STING-IN-2 (C-170; 0.5 μM) and stimulated with cGAMP. STING-IN-2 (C-170) treatment decreases the IFNB1 and TNF mRNA levels, and also reduces the p-TBK1 levels. |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 3.4686 mL | 17.3430 mL | 34.6861 mL | 69.3722 mL |
| 5mM | 0.6937 mL | 3.4686 mL | 6.9372 mL | 13.8744 mL |
| 10mM | 0.3469 mL | 1.7343 mL | 3.4686 mL | 6.9372 mL |
| 20mM | 0.1734 mL | 0.8672 mL | 1.7343 mL | 3.4686 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start)
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Volume(start)
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Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
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Volume(start)
V1
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Concentration(final)
C2
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Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.