cGAMP (Cyclic GMP-AMP)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100mg | $4715 | Check With Us |
| 200mg | $7070 | Check With Us |
| 500mg | $11930 | Check With Us |
: Cat #: V5330 CAS #: 849214-04-6 Purity ≥ 98%
Description: cGAMP (also known as Cyclic GMP-AMP; 3',3'-cGAMP) is a cyclic nucleotide acting as a STING agonist.
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- Physicochemical and Storage Information
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- Related Biological Data
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- Quality Control Documentation
| Molecular Weight (MW) | 674.41 |
|---|---|
| Molecular Formula | C₂₀H₂₄N₁₀O₁₃P₂ |
| CAS No. | 849214-04-6 |
| Storage | -20℃ for 3 years in powder formr |
| -80℃ for 2 years in solvent | |
| SMILES Code | O=C1N=C(NC2=C1N=CN2[C@@H]3O[C@H](COP(O)(O[C@H]4[C@H]([C@@H](O[C@@H]4CO5)N6C=NC7=C6N=CN=C7N)O)=O)[C@@H](OP5(O)=O)[C@H]3O)N |
| Synonyms | 3′3′-cGAMP; Cyclic AMP-GMP; c-GMP-AMP; cyclic GMP-AMP; cGAMP |
| Protocol | In Vitro | cGAMP promotes the antigen-specific proliferation capacity of spleen cells in mice. |
|---|---|---|
| In Vivo | cGAMP promotes the antigen-specific cytokine production by spleen cells of immunized mice. |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 1.4828 mL | 7.4139 mL | 14.8278 mL | 29.6556 mL |
| 5mM | 0.2966 mL | 1.4828 mL | 2.9656 mL | 5.9311 mL |
| 10mM | 0.1483 mL | 0.7414 mL | 1.4828 mL | 2.9656 mL |
| 20mM | 0.0741 mL | 0.3707 mL | 0.7414 mL | 1.4828 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.