Quinine is a naturally occuring anti-malaria agent which acts as a potassium channel inhibitor with an IC50 of 169 μM, also has antipyretic (fever-reducing), analgesic (painkilling), anti-inflammatory properties and a bitter taste.

Mesoridazine is a potent phenothiazine dopamine receptor anatagonist that is able to inhibit D2DR and D4DR.

Vonoprazan Fumarate (formerly TAK-438, TAK 438, trade name Takecab), the fumarate salt of Vonoprazan, is a novel, orally bioactive and potent P-CAB (potassium-competitive acid blocker) that has been approved in Janpan in 2015 for the treatment of gastroduodenal ulcer and reflux esophagitis.

This product has been discontinued. KPT-185 (KPT185; KPT 185) is an irreversible and selective CRM1 (Chromosomal Maintenance 1, also known as Exportin 1 or XPO1) inhibitor with potential antitumor activity.

Nicorandil (formerly RP46417; SG-75; SG75; RP-46417; Dancor and Adancor) is a potassium channel activator that has been approved as a vasodilatory drug to treat angina.

Pinacidil monohydrate, the monohydrated form of pinacidil, is an orally bioactive antihypertensive drug acting as a potassium channel activator.

XE991 diHCl (LS190926) is a novel, potent and selective blocker of KCNQ (Kv7) voltage-gated potassium channels.

Amiodarone HCl (formerly NSC-85442; NSC85442; NSC 85442; Cordarone), the hydrochloride salt of amiodarone, is an antiarrhythmic drug used to treat and prevent an irregular heartbeat.

VU0529331 is a novel, potent and modestly selective activator of non-GIRK1-containing G protein-gated, inwardly-rectifying, potassium channel (non-GIRK1/X) with EC50s of 5.1 µM and 5.2 µM for GIRK2 and GIRK1/2 in HEK293 cells, respectively.

Gliquidone (also known as AR-DF 26; Glurenorm; Beglynor) is a potent ATP-sensitive K+ channel antagonist with potential anti0diabetic activity.