Quinine
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 10g | $300 | Check With Us |
| 20g | $450 | Check With Us |
| 50g | $699 | Check With Us |
: Cat #: V7338 CAS #: 130-95-0 Purity ≥ 98%
Description: Quinine is a naturally occuring anti-malaria agent which acts as a potassium channel inhibitor with an IC50 of 169 μM, also has antipyretic (fever-reducing), analgesic (painkilling), anti-inflammatory properties and a bitter taste.
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| Molecular Weight (MW) | 324.42 |
|---|---|
| Molecular Formula | C20H24N2O2 |
| CAS No. | 130-95-0 |
| SMILES Code | COC1=CC2=C(C=CN=C2C=C1)C(C3CC4CCN3CC4C=C)O |
| Synonyms | Quinine; Chinin; Chininum; 6'-Methoxycinchonidine; (8S,9R)-Quinine; Qualaquin; Odan Brand of Quinine Sulfate; Plough Brand of Quinine Sulfate; Prosana Brand of Quinine Bisulfate; Quinamm; Quinbisan; Quinbisul; Quindan |
| Protocol | In Vitro | Quinine (37.5-150 μM, 24 hours) significantly reduces viral DENV RNA and protein levels in a dose-dependent manner in human hepatocarcinoma HepG2 cell line |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 3.0824 mL | 15.4121 mL | 30.8242 mL | 61.6485 mL |
| 5mM | 0.6165 mL | 3.0824 mL | 6.1648 mL | 12.3297 mL |
| 10mM | 0.3082 mL | 1.5412 mL | 3.0824 mL | 6.1648 mL |
| 20mM | 0.1541 mL | 0.7706 mL | 1.5412 mL | 3.0824 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.