Pinacidil monohydrate

This product is for research use only, not for human use. We do not sell to patients.

Pinacidil monohydrate
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
1g$500Check With Us
2g$800Check With Us
5g$1300Check With Us

Cat #: V29082 CAS #: 85371-64-8 Purity ≥ 99%

Description: Pinacidil monohydrate, the monohydrated form of pinacidil, is an orally bioactive antihypertensive drug acting as a potassium channel activator.

References: Bareggi SR, et al. Pharmacodynamics and pharmacokinetics of pinacidil in normotensive volunteers after repeated doses of a new slow-release tablet formulation. Arzneimittelforschung. 1999 Jan;49(1):21-5.

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Molecular Weight (MW)263.34
Molecular FormulaC₁₃H₂₁N₅O
CAS No.85371-64-8
ProtocolIn Vitro Pinacidil hydrate is an antihypertensive drug of the class of agents called "potassium channel openers
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.7974 mL18.9869 mL37.9737 mL75.9474 mL
5mM0.7595 mL3.7974 mL7.5947 mL15.1895 mL
10mM0.3797 mL1.8987 mL3.7974 mL7.5947 mL
20mM0.1899 mL0.9493 mL1.8987 mL3.7974 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.