Sapogenins glycosides are a mixture of triterpene and steroid saponins isolated from medicinal plants such as Aesculus hippocastanum L., Hedera helix L. and Ruscus aculeatus L., which are claimed to be effective for the treatment/prevention of venous insufficiency. Sapogenins are the aglycones, or non-saccharide, portions of the family of natural products known as saponins. They […]

Iprobenfos is a potent organophosphorus pesticide and fungicide widely used to control the rice blast fungus.

Isavuconazonium sulfate (formerly BAL-8557; BAL8557; isavuconazole; Cresemba), the sulfate salt of Isavuconazonium, is the prodrug of isavuconazole (BAL4815) which is an approved triazole-based antifungal drug.

Posaconazole (also known as SCH 56592 or trade name of Noxafil) is a potent, broad-spectrum, second generation triazole antifungal compound that potently inhibits 14α-demethylation in a variety of fungi, including Candida and Aspergillus, with half maximal inhibition concentration IC50 of 0.007 μg/ml, 0.06 μg/ml, 0.2 μg/ml, 0.3 μg/ml, 0.03 μg/ml and 0.03 μg/ml respectively Posaconzole, […]

Naftifine HCl (AW-105843; SN 105843) is an allylamine-based, synthetic, and broad spectrum antifungal drug for the topical treatment of tinea pedis, tinea cruris, and tinea corporis, probably involves selectively blocking sterol biosynthesis via inhibition of the squalene 2,3-epoxidase enzyme. Naftifine exhibits an interesting in vitro spectrum of activity against dermatophytes (38 strains; minimal inhibitory concentration […]

Nystatin (Candex;Mycostatin; Barstatin 100; Biofanal; AI3-26526) is a potent polyene antifungal antibiotic with a broad-spectrum fungicidal and fungistatic activity against a number of yeasts and fungi, most notably Candida species.

Triticonazole is a triazole-based fungicidal agent as well as a pesticide with broad antifungal and endocrine disrupting activities.

Econazole Nitrate (formerly also known as NSC-243115; SQ-13050; Spectazole) is a potent calcium channel blocker/CCB used as an imidazole-based antifungal medicine against infections caused by fungus. It was approved in 1974 for treating a variety of fungal skin infections such as athlete’s foot, jock itch, and ringworm. Econazole nitrate is an effective inducer of micronuclei […]

Mancozeb is a potent agricultural fungicide of the ethylene bisdithiocarbamate class.

Chlorothalonil (Daconil; DAC 2787; Tetrachloroisophthalodinitrile; Perchloroisophthalonitrile) is a broad spectrum antifungal agent and fungicide with carcinogenic and aquatic toxicity properties.