Nystatin

This product is for research use only, not for human use. We do not sell to patients.

Nystatin
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Size Price Stock
25g$650Check With Us
50g$950Check With Us
100g$1425Check With Us

Cat #: V32994 CAS #: 1400-61-9 Purity ≥ 99%

Description: Nystatin (Candex;Mycostatin; Barstatin 100; Biofanal; AI3-26526) is a potent polyene antifungal antibiotic with a broad-spectrum fungicidal and fungistatic activity against a number of yeasts and fungi, most notably Candida species.

References: Ellepola AN, et al. Adhesion of oral Candida species to human buccal epithelial cells following brief exposure to nystatin. Oral Microbiol Immunol. 1999 Dec;14(6):358-63.

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Molecular Weight (MW)926.09
Molecular FormulaC47H75NO17
CAS No.1400-61-9
SMILES Code O=C(O)[C@@H]1[C@H]2O[C@](O)(C[C@H](O)[C@H](O)CC[C@H](C[C@H](C[C@H](O)CC(O[C@H]([C@H](C)[C@@H]([C@H](/C=C/C=C/CC/C=CC=CC=CC=C[C@H](C2)O[C@@H]3[C@@H](O)[C@@H](N)[C@H](O)[C@@H](C)O3)C)O)C)=O)O)O)C[C@@H]1O
SynonymsNyotran; Nysert; Nystan; Nystatin; Nystatine; Nystavescent; Moronal; Myconystatin; Mycostatin; Nilstat; Nistatin; Mycostatin. AI3-26526; Barstatin 100; Nistatina; NSC 150817; Nyamyc; Nystatin; Biofanal; Candex; Herniocid; HSDB 3138; Korostatin; Candex Lotion; Candio-hermal; Nystex; Nystop; O-V Statin; Stamycin; Zydin E; Diastatin; Fungicidin;
ProtocolIn VitroNystatin results in a significant reduction in buccal epithelial cell adhesion of all six Candida species.
In VivoNystatin combined with endostatin selectively enhances endostatin uptake and biodistribution in tumor blood vessels and tumor tissues but not in normal tissues of tumor-bearing mice, ultimately resulting in elevated antiangiogenic and antitumor efficacies of endostatin in vivo.
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.0798 mL5.3990 mL10.7981 mL21.5962 mL
5mM0.2160 mL1.0798 mL2.1596 mL4.3192 mL
10mM0.1080 mL0.5399 mL1.0798 mL2.1596 mL
20mM0.0540 mL0.2700 mL0.5399 mL1.0798 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

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C2
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Volume(final)
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Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.