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Isavuconazonium sulfate (BAL8557)

This product is for research use only, not for human use. We do not sell to patients.

Isavuconazonium sulfate (BAL8557)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
250mg$960To Be Confirmed
500mg$1450To Be Confirmed
1g$2175To Be Confirmed

Cat #: V5313 CAS #: 946075-13-4 Purity ≥ 98%

Description: Isavuconazonium sulfate (formerly BAL-8557; BAL8557; isavuconazole; Cresemba), the sulfate salt of Isavuconazonium, is the prodrug of isavuconazole (BAL4815) which is an approved triazole-based antifungal drug.

References: Schmitt-Hoffmann AH, et al. Tissue Distribution and Elimination of Isavuconazole following Single and Repeat Oral-Dose Administration of Isavuconazonium Sulfate to Rats. Antimicrob Agents Chemother. 2017 Nov 22;61(12). pii: e01292-17.

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Product Promise

Promise
Molecular Weight (MW)814.84
Molecular FormulaC35H36F2N8O9S2
CAS No.946075-13-4
Storage-20℃ for 3 years in powder formr
-80℃ for 2 years in solvent
SMILES CodeC[C@@H](C1=NC(=CS1)C2=CC=C(C=C2)C#N)[C@](CN3C=[N+](C=N3)C(C)OC(=O)N(C)C4=C(C=CC=N4)COC(=O)CNC)(C5=C(C=CC(=C5)F)F)O.OS(=O)(=O)[O-]
SynonymsBAL8557; BAL 8557; BAL-8557; Isavuconazonium sulfate; isavuconazole; brand name: Cresemba.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.2272 mL6.1362 mL12.2723 mL24.5447 mL
5mM0.2454 mL1.2272 mL2.4545 mL4.9089 mL
10mM0.1227 mL0.6136 mL1.2272 mL2.4545 mL
20mM0.0614 mL0.3068 mL0.6136 mL1.2272 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.