Alexidine Dihydrochloride is a novel and potent inhibitor of PTPMT1 (Protein Tyrosine Phosphatase Localized to the Mitochondrion 1) with antibacterial and anti-plaque activity.
Cyclosporin C is a naturally occuring and highly lipophilic cyclic peptide, a member of the cyclosporin series of antifungal and immunosuppresive compounds – Cyclosporin A and B.
Caspofungin acetate (formerly known as MK-0991; trade name: Cancidas), a cyclic lipopeptide, is a new class of antifungal drug. It is a semi-synthetic analogue of pneumocandin B0 with improved water solubility, a significant limitation in the development of the echinocandin class as pharmaceuticals. Caspofungin acts by inhibiting the synthesis of β (1,3)-D-glucan, an essential component […]
Amorolfine HCl (Ro 14-4767/002), a topically administered drug, is a potent and broad-spectrum antifungal agent with fungicidal effects against most fungi, dermatophytes and yeasts. Amorolfine blocks ergosterol biosynthesis by interfering with delta 14 reduction and the delta 7-8 isomerisation. Amorolfine is an antifungal showing activity against fungi pathogenic to plants, animals and humans. At 0.2, […]
Bifonazole ( Bifomyk; Bay H-4502; Bifokey;Bifon) is a potent imidazole-based antifungal drug with a broad-spectrum of antimycotic activity by interfering with sterol biosynthesis.