Triflusal (formerly UR1501; Disgren, Grendis, Aflen, Triflux), a platelet aggregation inhibitor and a salicylate analog, acts by irreversibly inhibiting the production of thromboxane-B2 in platelets via acetylating the enzyme COX-1/cycloxygenase-1.
Etoricoxib (also known as MK-0663) is a non-steroidal anti-inflammatory drgu (NSAID) which acts as a selective and orally bioactive COX-2 inhibitor, with IC50s of 1.1 μM and 116 μM for COX-2 and COX-1 in human whole blood.
Etodolac (AY-24236, Etodolic Acid, AY24,236, AY24236, Lodine, Ramodar, Ultradol) is a potent nonsteroidal anti-inflammatory drug (NSAID) and a non-selective COX inhibitor with potential anti-inflammatory activity.
Naproxen Sodium (formerly RS 3650; RS-3650; Naproxen natrium), an approved non-steroidal anti-inflammatory drug (NSAID), is a nonselective COX inhibitor for COX-1 and COX-2 with potential anti-inflammatory activity.
Nabumetone (formerly BRL-14777; BRL14777; Relafen, Relifex, Gambaran, Arthraxan), a non-steroidal anti-inflammatory drug (NSAID), is a selective COX-2 inhibitor and a prodrug with potential anti-inflammatory activity.
Phenacetin (also known as acetophenetidin) is a potent non-opioid analgesic agent without anti-inflammatory properties.
Acemetacin (K708; Acemetacin; Rantudil; K-708; TVX 1322; TVX-1322) is a potent non-steroidal anti-inflammatory drug (NSAID) and a glycolic acid ester of indometacin that is a cyclooxygenase inhibitor with potential anti-inflammatory activity.
Tolfenamic Acid (formerly GEA 6414; GEA6414; GEA-6414; Clotam), a non-steroidal anti-inflammatory drugs (NSAIDs), is a potent and selective COX-2 inhibitor with potential anti-inflammatory activity.
Indomethacin (Indometacin; Indocin) is a potent and non-selective COX1 and COX2 inhibitor of the nonsteroidal anti-inflammatory drug (NSAID) class with an IC50 of 0.1 μg/mL and 5 μg/mL, respectively.
Celecoxib (formerly SC58635; YM-177; SC-58635; YM 177; trade name Celebrex; Xilebao), an anti-inflammatory agent of the NSAID class, is a potent and selective COX-2 inhibitor of the non-steroidal anti-inflammatory drug (NSAID) class with an IC50 of 40 nM in Sf9 cells.