NS-398 [also called NS 398, N-(2-cyclohexyloxy-4-nitrophenyl)methane sulfonamide] is a novel, highly potent and selective inhibitor of cyclooxygenase-2 (COX-2) that is used as a non-steroidal an-inflammatory agent with analgesic and antipyretic effects.

TFAP is a cell-permeable pyridinyl-benzamide compound that acts as a COX-1-selective inhibitor by targeting the enzyme’s active site.

Anemarsaponin B is a naturally occuring steroidal saponin extracted from the rhizomes of A. asphodeloides (Liliaceae).

Iguratimod (T614; T-614) is a 4H-1-benzopyran-based antirheumatic agent acting as a novel and potent nhibitor of COX-2 (IC50 = 20 μM) with no effect on COX-1.

Lumiracoxib (formerly CGS-35189; COX-189; trade name Prexige), a non-steroidal anti-inflammatory drug (NSAID), is a selective COX-2 enzyme inhibitor with potential anti-inflammatory activity.

Valdecoxib (SC-65872; SC65872; SC 65872; Bextra), a nonsteroidal anti-inflammatory drug (NSAID), is a potent and selective inhibitor of COX-2 enzyme with potential anti-inflammatory activity.

Flunixin Meglumin (Banamine; Flumeglumine; Flunixin-S), a non-steroidal anti-inflammatory drug (NSAID), is a potent inhibitor of the enzyme COX-cyclooxygenase with analgesic, anti-inflammatory and antipyretic activities.

Oxaprozin (Oxaprozinum, DL-8280, WY-21743; DR-3355, Hoe-280, ORF-28489, Ru-43280, Tarivid) is a potent nonsteroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties.

Niflumic acid (Flunir, Donalgin, Niflactol, Niflugel, Nifluril) is a potent inhibitor of cyclooxygenase-2 (COX-2) enzyme with potential anti-inflammatory and analgesic activity.

Ketorolac (Toradol, Acular, RS 37619; RS37619; Sprix, Macril, Acuvail, Lixidol), an NSAID (non-steroidal anti-inflammatory drug), is a potent and non-selective COX inhibitor of COX-1 and COX-2 with potential anti-inflammatory activity.