Piroxicam (formerly BAXO; CP16171; CP-16171; Feldene; Pyroxycam; Roxicam), an approved non-steroidal anti-inflammatory drug (NSAID), is a potent and non-selective COX inhibitor with potential anti-inflammatory activity.

Amfenac Sodium monohydrate (AHR 5850; AHR5850; AHR5850), the sodium salt of amfenac which is an NSAID, is a non-steroidal analgesic anti-inflammatory agent with antipyretic and analgesic activities.

Meclofenamate Sodium (Meclonax; Meclomen; INF-4668; INF4668; CI 583; CI-583; Meclodium; Meclofenamic acid sodium) is a potent nonsteroidal anti-inflammatory drug (NSAID), acting as a dual COX-1/COX-2 inhibitor with IC50 of 40 nM and 50 nM, respectively.

Nepafenac (formerly AHR9434; AL 6515; AL-6515; AHR-9434; Nevanac; Nevanac) is a potent non-steroidal anti-inflammatory drug (NSAID), and a prodrug of amfenac that acts as an inhibitor of COX-1 and COX-2 enzyme activity.

Carprofen (Rimadyl; Ro-205720; C 5720; quellin; Novox; Imafen; Rovera), a nonsteroid anti-inflammatory drug (NSAID), is a potent and multi-target FAAH/COX inhibitor with potential anti-inflammatory activity.

Lornoxicam (Chlortenoxicam; Xefo; Lornoxicamum; Xefocam; TS-110; Ro 13-9297; TS110), a non-steroidal anti-inflammatory drug (NSAID), is a potent COX-1/COX-2 inhibitor with potential anti-inflammatory activity.

Ibuprofen Lysine (Arflamin, Ibuprofen lysinate, NeoProfen, Saren), the pyridyl ester of ibuprofen, is an anti-inflammatory drug that belongs to the non-steroidal anti-inflammatory drug (NSAIDs) class.

Bufexamac (formerly also known as CP-1044-J-3; CP1044J3; Droxaryl; Parfenac; Bufexamic acid), a non-steroidal anti-inflammatory drug/NSAID, is a potent COX enzyme inhibitor with potential anti-inflammatory activity.

Zaltoprofen (CN 100; CN-100; CN100), a nonsteroidal anti-inflammatory drug (NSAID), is a potent inhibitor of COX-1 and COX-2 enzymes with potential anti-inflammatory activity.

Meloxicam (Parocin; Movicox; Meloxicamum; Mobic; Mobicox; reumoxicam; Movalis; Uticox), an approved medication used to treat pain and inflammation in rheumatic arthritis and osteoarthritis, is a potent non-steroidal anti-inflammatory drug (NSAID) which acts as a selective COX inhibitor with IC50s of 0.49 µM and 36.6 µM for COX-2 and COX-1, respectively.