Carprofen
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 5g | $600 | Check With Us |
| 10g | $980 | Check With Us |
| 20g | $1470 | Check With Us |
: Cat #: V1074 CAS #: 53716-49-7 Purity ≥ 98%
Description: Carprofen (Rimadyl; Ro-205720; C 5720; quellin; Novox; Imafen; Rovera), a nonsteroid anti-inflammatory drug (NSAID), is a potent and multi-target FAAH/COX inhibitor with potential anti-inflammatory activity.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 273.71 |
|---|---|
| Molecular Formula | C15 H12ClNO2 |
| CAS No. | 53716-49-7 |
| Storage | -20℃ for 3 years in powder formrr |
| -80℃ for 2 years in solvent | |
| Solubility In Vitro | DMSO: 55 mg/mL (200.9 mM)rr |
| Water: <1 mg/mLrr | |
| Ethanol: 55 mg/mL (200.9 mM) | |
| SMILES Code | CC(C1=CC2=C(C=C1)C3=C(N2)C=CC(=C3)Cl)C(=O)O |
| Synonyms | Ro205720; C-5720; Ro 205720; C5720; Carprofen; Imadyl; Rimadyl; Ridamyl; Ro 20-5720; C 5720; Imadyl; quellin; Novox; Imafen; Rovera |
| Protocol | In Vivo | Carprofen (2.2 mg/kg, po) significantly reduced PGE3 concentrations in dog blood on days 10 and 2. Carprofen also reduced gastric PGE3 synthesis on day 2, but inhibition was not significant on day 10. In addition, Carprofen showed no activity on gastric PGE3 synthesis in dogs on days 10 and 1 |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 3.6535 mL | 18.2675 mL | 36.5350 mL | 73.0700 mL |
| 5mM | 0.7307 mL | 3.6535 mL | 7.3070 mL | 14.6140 mL |
| 10mM | 0.3654 mL | 1.8268 mL | 3.6535 mL | 7.3070 mL |
| 20mM | 0.1827 mL | 0.9134 mL | 1.8268 mL | 3.6535 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.