Mavacoxib (PHA-739521), a long-acting non-steroidal anti-inflammatory drug (NSAID), is a selective, orally active and long-acting cyclooxygenase-2 (COX-2) inhibitor used to treat pain and inflammation associated with degenerative joint disease in dogs.

Desmethyl Celecoxib (PTPBS) is an demethylated metabolite of Celecoxib (SC58635; YM-177; SC-58635; YM 177; Celebrex; Xilebao) which is cyclooxygenase-2 (COX-2) inhibitor approved as an anti-inflammatory agent of the NSAID class.

Deracoxib (SC-046; SC-46; SC-59046) is a novel and potent NSAID and COX-2 inhibitor used to treat osteoarthritis.

Isoorientin is a novel and potent inhibitor of COX-2.

Rutaecarpine (also known as rutecarpine; Rutacarpine; Rutaecarpin; Rhetine) is a naturally occuring indolopyridoquinazolinone alkaloid isolated from isolated from the chinese herb Evodia rutaecarpa which has vasorelaxing effect and inhibits platelet aggregation and Cox-2.

FK3311 is a cyclooxygenase-2 (COX-2) inhibitor.

Ketorolac tromethamine (RS37619 tromethamine), potent NSAID (non-steroidal anti-inflammatory drug), is a potent and non-selective COX inhibitor of COX-1 and COX-2 with IC50 of 1.23 μM and 3.50 μM, respectively.

Flurbiprofen, a phenylalkanoic acid derivative, belongs to the class of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs) with antipyretic and analgesic activity.

Naproxen (also known as (S)-Naproxen)) is a non-steroidal anti-inflammatory drug (NSAID) which is a nonselective COX inhibitor for COX-1 and COX-2 with IC50 of 8.7 μM and 5.2 μM, respectively.

FR-122047 HCl (FR 122047; FR122047), the hydrochloride salt of FR-122047, is a novel, potent and selective cyclooxygenase-1 (COX-1) inhibitor with potential anticancer activities.