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Bufexamac (Bufexamic acid)

This product is for research use only, not for human use. We do not sell to patients.

Bufexamac (Bufexamic acid)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
10g$550Check With Us
25g$950Check With Us
50g$1425Check With Us

Cat #: V1063 CAS #: 2438-72-4 Purity ≥ 98%

Description: Bufexamac (formerly also known as CP-1044-J-3; CP1044J3; Droxaryl; Parfenac; Bufexamic acid), a non-steroidal anti-inflammatory drug/NSAID, is a potent COX enzyme inhibitor with potential anti-inflammatory activity.

References: Bantscheff, M., et al., Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes. Nat Biotechnol, 2011. 29(3): p. 255-65.

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Product Promise

Promise
Molecular Weight (MW)223.27
Molecular FormulaC12H17NO3
CAS No.2438-72-4
Storage-20℃ for 3 years in powder formrr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 45 mg/mL (201.5 mM)rr
Water: <1 mg/mLrr
Ethanol: 3 mg/mL (13.4 mM)
SMILES CodeO=C(NO)CC1=CC=C(OCCCC)C=C1
SynonymsCP 1044 J 3; Bufexamic acid; CP-1044-J-3; CP1044J3; Droxaryl; Parfenac
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM4.4789 mL22.3944 mL44.7888 mL89.5776 mL
5mM0.8958 mL4.4789 mL8.9578 mL17.9155 mL
10mM0.4479 mL2.2394 mL4.4789 mL8.9578 mL
20mM0.2239 mL1.1197 mL2.2394 mL4.4789 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.