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Amfenac Sodium Monohydrate

This product is for research use only, not for human use. We do not sell to patients.

Amfenac Sodium Monohydrate
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Size Price Stock
1g$390Check With Us
2g$590Check With Us
5g$900Check With Us

Cat #: V1075 CAS #: 61618-27-7 Purity ≥ 98%

Description: Amfenac Sodium monohydrate (AHR 5850; AHR5850; AHR5850), the sodium salt of amfenac which is an NSAID, is a non-steroidal analgesic anti-inflammatory agent with antipyretic and analgesic activities.

References: Marshall JC, et al. The effects of a cyclooxygenase-2 (COX-2) expression and inhibition on human uveal melanoma cell proliferation and macrophage nitric oxide production. J Carcinog. 2007 Nov 27;6:17.

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Molecular Weight (MW)295.27
Molecular FormulaC15H12NO3.H2O.Na
CAS No.61618-27-7
Storage-20℃ for 3 years in powder formrr
-80℃ for 2 years in solvent
Solubility In VitroDMSO: 59 mg/mL (199.8 mM)rr
Water: 59 mg/mL (199.8 mM)rr
Ethanol: 4 mg/mL (13.5 mM)
SMILES CodeO=C([O-])CC1=CC=CC(C(C2=CC=CC=C2)=O)=C1N.[H]O[H].[Na+]
SynonymsAHR 5850; AHR5850; AHR5850
ProtocolIn VitroCells transfected to express COX-2 have a higher proliferation rate than those do not. The addition of Amfenac Sodium Hydrate significantly decreases the proliferation rate of all cell lines. Nitric oxide production by macrophages is inhibited by the addition of melanoma conditioned medium, the addition of Amfenac Sodium Hydrate partially overcomes this inhibition
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.3867 mL16.9337 mL33.8673 mL67.7346 mL
5mM0.6773 mL3.3867 mL6.7735 mL13.5469 mL
10mM0.3387 mL1.6934 mL3.3867 mL6.7735 mL
20mM0.1693 mL0.8467 mL1.6934 mL3.3867 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.