Iguratimod
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
Size | Price | Stock |
---|---|---|
100mg | $550 | Check With Us |
250mg | $900 | Check With Us |
500mg | $1350 | Check With Us |
Cat #: V17597 CAS #: 123663-49-0 Purity ≥ 99%
Description: Iguratimod (T614; T-614) is a 4H-1-benzopyran-based antirheumatic agent acting as a novel and potent nhibitor of COX-2 (IC50 = 20 μM) with no effect on COX-1.
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Molecular Weight (MW) | 374.37 |
---|---|
Molecular Formula | C17H14N2O6S |
CAS No. | 123663-49-0 |
SMILES Code | O=CNC1=COC2=C(C=C(OC3=CC=CC=C3)C(NS(=O)(C)=O)=C2)C1=O |
Synonyms | Iguratimod |
Solvent volume to be added | Mass (the weight of a compound) | |||
---|---|---|---|---|
Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
1mM | 2.6712 mL | 13.3558 mL | 26.7115 mL | 53.4231 mL |
5mM | 0.5342 mL | 2.6712 mL | 5.3423 mL | 10.6846 mL |
10mM | 0.2671 mL | 1.3356 mL | 2.6712 mL | 5.3423 mL |
20mM | 0.1336 mL | 0.6678 mL | 1.3356 mL | 2.6712 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.