Clavulanate lithium (Augmentin) is a β-lactamase inhibitor and antibiotic used in combination with amoxicillin for bacterial infections.

GSK2200150A is a novel and potent antimycobacterial agent that has the potential for the treatment of tuberculosis (TB). It has activity against Mycobacterium tuberculosis and Mycobacterium bovis BCG. Tuberculosis afflicts an estimated 2 billion people worldwide and causes 1.3 million deaths annually. Chemotherapeutic solutions rely on drugs developed many years ago, with only one new […]

Edoxudine is an analog of thymidine and antiviral agent with activity in hairless mice infected with herpes simplex virus 1.

Iodoquinol (also known as Diiodohydroxyquinoline), a halogenated 8-quinolinol analog with satisfactory antibacterial properties, is widely used as an intestinal antiseptic, especially as an antiamebic agent.

Erythromycin is a potent and broad-spectrum antibiotic belonging to a group of drugs called macrolide antibiotics, it is produced by actinomycete Streptomyces erythreus and is an inhibitor of protein translation and mammalian mRNA splicing.

Methylprednisolone sodium succinate (U-9088; 6α-Methylprednisolone 21-hemisuccinate sodium) is a water-soluble ester of Methylprednisolone (also known as NSC-19987) which is a synthetic and potent glucocorticoid receptor agonist, used to achieve prompt suppression of inflammation.

N-Acetyl-Calicheamicin (N-Acetyl-Calicheamicin γ; N-Acetyl-γ-calicheamicin), the N-acetylated analog of calicheamicin, is a novel and potent antitumor antibiotic of the enediyne class.

CHIR-090 (CHIR090), a novel N-aroyl-l-threonine hydroxamic acid and antibiotic, is a highly potent, slow, and tight-binding inhibitor of the LpxC deacetylase from the hyperthermophile Aquifex aeolicus. LpxC is a deacetylase involved in the biosynthesis of LPS lipid A. CHIR-090 has excellent antibiotic activity against Pseudomonas aeruginosa and Escherichia coli, as judged by disk diffusion assays. […]

Ertapenem sodium (MK-0826; L-749345; Invanoz; Invanz), the sodium salt of ertapenem, is a 1-β-methyl carbapenem antibiotic marketed by Merck as Invanz. Ertapenem is a long-acting, broad-spectrum antibiotic of β-lactam subclass. Ertapenem has a broad spectrum of antibacterial activity including common aerobic and anaerobic bacteria and organisms with extended-spectrum β-lactamases. Ertapenem is an inhibitor of bacteria […]

Nosiheptide is a parent compound of thiopeptide family that exhibit potent activities against various bacterial pathogens.