Puromycin 2HCl (CL13900), an analog of aminoacyl-tRNA (anaminonucleoside), is a potent antibiotic which acts as a protein synthesis inhibitor. It inhibits the incorporation of aminoacyl-tRNA into the C-terminal on a synthesizing polypeptide, resulting in the premature termination of the polypeptide chain. Puromycin is toxic to the growth of various eukaryote cells including mammalian cells. Concentrations […]

Fusidic Acid (Fucidin; SQ-16603), a bacteriostatic antibiotic isolated from the Fusidium coccineum fungus, is a protein synthesis inhibitor of the steroidal class used to treat bacterial infections.

Lomefloxacin Hydrochloride (DM10; CCRIS6305) is a novel and potent fluoroquinolone antibiotic widely used for treating bacterial infections, such as bronchitis and urinary tract infections.

Tiamulin fumarate is a novel and potent diterpenic veterinary drug.

Sultamicillin Tosylate, the tosylate salt form of Sultamicillin which is a double ester of sulbactam and ampicillin. Sultamicillin (formerly known as CP-49952 and VD 1827) is an orally available, mutual prodrug form of ampicillin and sulbactam. As an antibiotic combination (co-drug or mutual prodrug) of ampicillin/sulbactam, it contains esterified ampicillin and sulbactam and is marketed […]

Ampicillin [D-(-)-α-Aminobenzylpenicillin)] is a potent broad-spectrum beta-lactam antibiotic widely used to prevent and treat a number of bacterial infections, such as respiratory tract infections, urinary tract infections, meningitis, salmonellosis, and endocarditis.

Rifabutin (also known as Ansamycin) is a semisynthetic ansamycin and broad-spectrum antibiotic with potent antimycobacterial properties.

Apramycin (also known as Ai3-29795; Nebramycin II) is a broad spectrum and aminoglycoside class of antibiotic, which binds to the deep groove of the RNA. Apramycin consumption at farm level is most probably driving the increasing occurrence of apramycin/gentamicin cross-resistant [aac(3)-IV positive] E. coli in diseased pigs and healthy finishers at slaughter. Apramycin inhibits A. […]

Cefoselis (also known as FK 037 Sulfate) is a widely used beta-lactam antibiotic of the cephalosporin class. Cefoselis inhibits GABA-induced currents in a concentration-dependent manner with IC50 of 185 mM. Cefoselis possesses a superior antistaphylococcal activity on MSSA isolates to both other compounds being however equal active to Cefepime and Cefpirome on multiresistant enterobacteriaceae. Cefoselis […]

Walrycin B is a potent WalR inhibitor.