Methylprednisolone sodium succinate

This product is for research use only, not for human use. We do not sell to patients.

For small sizes, please check our retail website as below: www.invivochem.com

Size	Price	Stock
250mg	$450	Check With Us
500mg	$750	Check With Us
1g	$1125	Check With Us

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Cat #: V11390 CAS #: 2375-03-3 Purity ≥ 98%

Description: Methylprednisolone sodium succinate (U-9088; 6α-Methylprednisolone 21-hemisuccinate sodium) is a water-soluble ester of Methylprednisolone (also known as NSC-19987) which is a synthetic and potent glucocorticoid receptor agonist, used to achieve prompt suppression of inflammation.

References: Cheng S, Gao W, Xu X, et al. Methylprednisolone sodium succinate reduces BBB disruption and inflammation in a model mouse of intracranial haemorrhage. Brain Res Bull. 2016;127:226-233.

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Quality Control Documentation

Molecular Weight (MW)	496.53
Molecular Formula	C26H33NaO8
CAS No.	2375-03-3
SMILES Code	O=C([O-])CCC(OCC([C@@](O)(CC1)[C@](C[C@H](O)[C@@H]2[C@@]3(C)C=C4)(C)[C@@H]1[C@@H]2C[C@H](C)C3=CC4=O)=O)=O.[Na+]
Synonyms	U 9088; U-9088; U9088; Methylprednisolone sodium succinate;

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	2.0140 mL	10.0699 mL	20.1398 mL	40.2795 mL
5mM	0.4028 mL	2.0140 mL	4.0280 mL	8.0559 mL
10mM	0.2014 mL	1.0070 mL	2.0140 mL	4.0280 mL
20mM	0.1007 mL	0.5035 mL	1.0070 mL	2.0140 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.