Ajmaline (also known as Gilurytmal and Ritmos) is a natual alkaloid and a sodium channel blocker.

Camostat mesylate (also known as FOY-305; FOY-S980), the mesylate salt of Camostat, is a potent and orally bioactive trypsin-like protease inhibitor with potential antifibrotic activity.

Eleclazine hydrochloride (also known as GS-6615) is a novel late Na+ current inhibitor with IC50 value of 0.7 uM.

Mexiletine HCl (Mexitil, Mexiletene, KO-1173, KO 1173; KO1173), the hydrochloride salt of Mexiletine, is an anti-arythmic drug of the Class IB group approved for use in the treatment of abnormal heart rhythms.

Digoxin (12β-Hydroxydigitoxin; Dixina; HSDB-214; Novodigal; Lanoxin PG; SK-Digoxin; Cardiogoxin) is a sodium-potassium pump inhibitor and a cardiotonic glycoside that has been approved for use in the treatment of various heart conditions such as arrhythmia and heart failure.

Raxatrigine (also known as GSK1014802 and CNV-1014802) is a novel, potent small molecule state-dependent sodium channel blocker, the Nav1.7 sodium channel inhibitor.

A-803467 (A803467; A 803467) is a novel, potent and selective NaV1.8 sodium channel blocker with potential analgesic effects.

GNE-131 is a novel, potent and selective inhibitor of human sodium channel NaV1.7, with an IC50 of 3 nM.

Raxatrigine (also known as GSK-1014802 and CNV-1014802) is a novel, potent small molecule state-dependent sodium channel blocker, the Nav1.7 sodium channel inhibitor.

Benzocaine (H-4-Abz-OEt; NSC-4688; NSC-41531; trade name Orajel among others), the ethyl ester of p-aminobenzoic acid (PABA), is a local anesthetic that has been widely used as a topical pain reliever or in cough drops.