Ajmaline
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 500mg | $350 | Check With Us |
| 1g | $550 | Check With Us |
| 5g | $1488 | Check With Us |
: Cat #: V10593 CAS #: 4360-12-7 Purity ≥ 99%
Description: Ajmaline (also known as Gilurytmal and Ritmos) is a natual alkaloid and a sodium channel blocker.
Top Publications Citing Invivochem Products
Publications Citing InvivoChem Products
Product Promise
- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 326.44 |
|---|---|
| Molecular Formula | C20H26N2O2 |
| CAS No. | 4360-12-7 |
| SMILES Code | CN1[C@]2([C@@]3(C[C@H]4[C@@H]([C@H](O)N3[C@@H]5[C@H]4[C@@H](O)[C@@]2(C6=C1C=CC=C6)C5)CC)[H])[H] |
| Synonyms | Tachmalin; Siddiqui; Takycor; Cardiorythmine; NSC 15627; Rauwolfin; (+)-Ajmaline; Raugalline; Rauwolfine; Ritmos; Gilurytmal; Merabitol; Ignazin; Rhytmaton; Rytmalin |
| Protocol | In Vitro | Electrophysiological experiments are performed with human embryonic kidney (HEK) cells (whole-cell patch clamp) and Xenopus oocytes (double-electrode voltage clamp) expressing wild-type and mutant HERG channels. Ajmaline blocks HERG currents with an IC50 of 1.0μM in HEK cells and 42.3μM in Xenopus oocytes |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 3.0634 mL | 15.3168 mL | 30.6335 mL | 61.2670 mL |
| 5mM | 0.6127 mL | 3.0634 mL | 6.1267 mL | 12.2534 mL |
| 10mM | 0.3063 mL | 1.5317 mL | 3.0634 mL | 6.1267 mL |
| 20mM | 0.1532 mL | 0.7658 mL | 1.5317 mL | 3.0634 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.