Amiloride HCl dihydrate (MK870; MK-870; MK 870; Midamor; Midoride; Modamide), the hydrochloride salt and dihydrated form of amiloride, is a potent and selective epithelial sodium channel (ENaC) blocker that has been used since 1967 in the management of hypertension and congestive heart failure.
ICA-121431 is a potent, highly selective small molecule inhibitor of the human Nav1.3 and Nav1.1 voltage gated sodium channels with IC50 of 19 nM.
Procaine HCl (also known as Novocaine; Gerovital H3; Aminocaine), the HCl salt of Procaine, is a local anesthetic that acts as an inhibitor of sodium channel, NMDA receptor and nAChR with IC50 of 60 μM, 0.296 mM and 45.5 μM.
Rufinamide (also known as CGP-33101; E-2080; RUF-331; BANZEL; Inovelon) is a voltage-gated sodium channel blocker approved as an antiepilepic agent for seizure treatment.
QX-314 Br is a novel intracellular blocker of NaV channels1-4 and a membrane impermeable quaternary analogue of lidocaine, a blocker of voltage-activated Na+ channels.
Phenazopyridine HCl is a local analgesic agent used in the urinary tract infections/UTIs to alleviate the pain, irritation, discomfort, or urgency.
Dibucaine HCl (also called Cincain; Nupercainal; Nupercaine; Sovcaine; Cinchocaine), the hydrochloride salt of dibucaine which is a sodium channel inhibitor, is one of the most potent and toxic of the long-acting local anesthetics.
BI01383298 (also known as BI-01383298) is a potent, specific/selective inhibitor of human SLC13A5 (Na+/citrate co-transporter) with IC50 of 56 nM in HEK cells overexpressing hSLC13A5 and 24 nM in HepG2 cells with endogenous SLC13A5 expression.
Ambroxol HCl (formerly NA872; NA 872; Abrohexal; Ebromin; Ambril; Ambro-Puren Ambrobeta; Duramucal; Mucosolvan), the hydrochloride salt of ambroxol, is a secretolytic agent that has been used in the treatment of respiratory diseases associated with viscid or excessive mucus.
Ropivacaine HCl hydrate is a novel and potent bioactive compound.