PROTAC PARP1 degrader is a PROTAC degrader

ACBI1 is a novel and potent PROTAC-based degrader of BAF ATPase subunits SMARCA2 and SMARCA4, it also degrades the polybromo-associated BAF (PBAF) complex member PBRM1

BSJ-4-116 is a novel, potent and selective CDK12 degrader (PROTAC)( IC50 = 6 nM).

E3 ligase Ligand-Linker Conjugates 37 Hydrochloridecomprises of an cIAP1 ligand for the E3 ubiquitin ligase and a PROTAC linker.

CM11 is a PROTAC molecule that acts as a novel and potent VHL inhibitor which induces complete degradation/depletion of pVHL30.

MZ 1 (MZ1; MZ-1) is a novel and potent PROTAC-based degrader of BRD4 protein with anticancer activity.

E3 ligase Ligand-Linker Conjugates 30 TFAcomprises of a cereblon ligand for the E3 ubiquitin ligase and a PROTAC linker.

E3 ligase Ligand-Linker Conjugates 32 hydrochloride is a lenalidomide-based ligand used in the recruitment of CRBN protein.

dCBP-1 is a novel, potent and selective heterobifunctional and PROTAC degrader of p300/CBP with potential anticancer activity.

RAR ligand 1 (Ch55-O-C3-carbaldehyde) is a warhead targeting RAR for degradation, used in PROTAC technology.