CORM-3 is a water-soluble carbon monoxide (CO)-releasing molecule with potent anti-inflammatory and cardioprotective activity by attenuatingNF-κB p65 nuclear translocation, reducing ROS generation and enhancing intracellular glutathione and superoxide dismutase levels.
Isolated from the Cassia obtusifolia seeds, Obtusifolin is natural product of the anthraquinone class.
Withaferin A, a steroidal lactone class of NFkB/IkB Inhibitor, is a natural product extracted from Acnistus arborescens,Withania somnifera (Indian Winter cherry or Ashwagandha in Sanskrit) and other members of Solanaceae family.
DCZ0415 (DCZ-0415; DCZ 0415) is a novel and highly potent TRIP13 inhibitor that is able to impair nonhomologous end joining repair and inhibits NF-κB activity.
Bay 65-1942 HCl is the hydrochloride salt of of BAY65-1942 which is a novel, potent and selective ATP-competitive inhibitor of IKKβ.
Hederagenin is a novel and potent organophosphate pesticide.
Avicularin is a novel and potent flavonoid.
Eleutheroside E is a novel and potent bioactive compound.
Triptolide (also known as NSC 163062), a diterpene triepoxide, is an immunosuppresive agent extracted from the Chinese herb Tripterygium wilfordii.
Evodiamine (d-Evodiamine; Q-100579; SC-16015; Evo; Isoevodiamine) is a naturally occuring quinazolinocarboline alkaloid extracted from the fruit of Evodiae Fructus, exhibiting moderate antiproliferative activities against various human tumor cells.