Avicularin
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100mg | $1120 | Check With Us |
| 200mg | $1680 | Check With Us |
| 500mg | $2835 | Check With Us |
: Cat #: V30086 CAS #: 572-30-5 Purity ≥ 99%
Description: Avicularin is a novel and potent flavonoid.
Top Publications Citing Invivochem Products
Publications Citing InvivoChem Products
Product Promise
- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 434.35 |
|---|---|
| Molecular Formula | C20H18O11 |
| CAS No. | 572-30-5 |
| SMILES Code | O=C1C(O[C@@H]2O[C@H]([C@@H]([C@H]2O)O)CO)=C(OC3=CC(O)=CC(O)=C13)C4=CC(O)=C(O)C=C4 |
| Synonyms | Avicularin; Quercetin 3-O-α-L-arabinofuranoside |
| Protocol | In Vitro | Avicularin (10-300 μM, 1 h) exhibits anti-inflammatory activity through the suppression of ERK signaling pathway in LPS-stimulated RAW 264.7 cells. Avicularin (10-300 μM, 1 h) suppresses NO and PGE2 production in LPS-stimulated RAW 264.7 cells. |
|---|---|---|
| In Vivo | Avicularin (injected in articular cavity of the knee, 0.5-2 mg/kg, twice a week for 4 weeks) attenuates the development of OA (osteoarthritis) in ACLT-induced rats. |
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 2.3023 mL | 11.5115 mL | 23.0229 mL | 46.0458 mL |
| 5mM | 0.4605 mL | 2.3023 mL | 4.6046 mL | 9.2092 mL |
| 10mM | 0.2302 mL | 1.1511 mL | 2.3023 mL | 4.6046 mL |
| 20mM | 0.1151 mL | 0.5756 mL | 1.1511 mL | 2.3023 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.