Adelmidrol is a diethanolamide derivative of azelaic acid that exerts potent anti-inflammatory effects that are partly dependent on PPARγ.

Kaempferol-3-O-glucorhamnoside (astragalin) is a naturally occuring and bioactive flavonoid found in plant Thesium chinense Turcz, that inhibits inflammatory responses via MAPK and NF-κB pathways in vitro and in vivo.

Parthenolide, formerly known as NSC-157035, is a novel sesquiterpene lactone isolated from the medicinal herb Feverfew, acting as a NF-κB activation inhibitor potentially for the treatment of cancer.

Sinomenine, a naturally occuring alkaloid isolated from the root of the plant Sinomenium acutum, is a blocker of the NF-κB activation with anticancer and anti-inflammatory effects.

Ammonium pyrrolidine dithiocarbamate (also abbreviated as PDTC) is a potent nuclear factor-κB (NF-κB) inhibitor.

(-)-Armepavine is a reticuline-like agent with antifibrotic effects.

C25-140 (C-25140; C25140) is a novel, first-in-class and potent inhibitor of RING-E3 ligase (TRAF6) / E2 enzyme (Ubc13) protein-protein interaction (PPI) with potential use for autoimmune and chronic inflammatory diseases.

Sodium salicylate (Magsalyl; Kerasalicyl; Kerosal), the sodium salt of salicylic acid and a metabolite of acetylsalicylic acid, is an inhibitor of NF-kB with potential anti-inflammatory activity.

JSH-23 (JSH23; JSH 23) was designed as a nove and potent inhibitor of NF-κB transcriptional activity with potential anti-inflammatory and anti-diabetic activity.

CBL0137 (formerly known as Curaxin 137 or CBL-0137) is an inhibitor of the histone chaperone, FACT (facilitates chromatin transcription complex).