Ethacrynic acid (MK-595; NSC-624008; NSC-85791; Hydromedin; Crinuryl; Mingit; Etacrinic acid; Otacril Reomax; Taladren; Edecrin) is a high ceiling loop diuretic acting as a Na+/K+/2Cl- cotransporter NKCC2 inhibitor.

Sulfasalazine (NSC-667219) is an approved antiinflammatory drug used for the treatment of rheumatoid arthritis, inflammatory bowel disease such as including ulcerative colitis and Crohn’s disease.

Dehydroevodiamine is a naturally occurring quinazoline alkaloid isolated from the unripe fruit of Evodia rutaecarpa (Rutaceae) with a variety of biological effects such as hypotensive, negative chronotropic, ion channel depressa.

Isoginkgetin is a novel and potent natural splicing inhibitor.

Berbamine is a naturally occuring isoquinoline alkaloid found in traditional Chinese medicine Barberry with anti-tumor, immunomodulatory and cardiovascular effects.

Indole-3-carbinol (I3C; 3-Indolemethanol) is natural product produced by the breakdown of the glucosinolate glucobrassicin, which can be found at relatively high levels in cruciferous vegetables.

INVIVO6620 is a novel and potent BTYNB IMP1 Inhibitor.

Isovitexin is a novel and potent glycosylated flavonoid.