Triptolide (PG490)
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
Size | Price | Stock |
---|---|---|
250mg | $950 | Check With Us |
500mg | $1550 | Check With Us |
1g | $2325 | Check With Us |
Cat #: V2079 CAS #: 38748-32-2 Purity ≥ 98%
Description: Triptolide (also known as NSC 163062), a diterpene triepoxide, is an immunosuppresive agent extracted from the Chinese herb Tripterygium wilfordii.
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Molecular Weight (MW) | 360.41 |
---|---|
Molecular Formula | C20H24O6 |
CAS No. | 38748-32-2 |
Storage | -20℃ for 3 years in powder formr |
-80℃ for 2 years in solvent | |
Solubility In Vitro | DMSO: 72 mg/mL (199.8 mM)r |
Water: <1 mg/mLr | |
Ethanol: <1 mg/mL | |
SMILES Code | O=C(OC1)C2=C1[C@@](C[C@H]3[C@]4(O3)[C@@]5(O6)[C@@H]6[C@H](O7)[C@@]7(C(C)C)[C@H]4O)([H])[C@]5(C)CC2 |
Synonyms | NSC163062; NSC-163062; NSC 163062; PG490; PG-490; PG 490; Tripterygium wilfordii. |
Solvent volume to be added | Mass (the weight of a compound) | |||
---|---|---|---|---|
Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
1mM | 2.7746 mL | 13.8731 mL | 27.7462 mL | 55.4924 mL |
5mM | 0.5549 mL | 2.7746 mL | 5.5492 mL | 11.0985 mL |
10mM | 0.2775 mL | 1.3873 mL | 2.7746 mL | 5.5492 mL |
20mM | 0.1387 mL | 0.6937 mL | 1.3873 mL | 2.7746 mL |
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start)
×
Volume(start)
=
Concentration(final)
×
Volume(final)
This equation is commonly abbreviated as: C1 V1 = C2 V2
Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.