GI254023X (also known as GI4023 and SRI028594) is a novel and potent inhibitor of MMP9 (Matrix Metallopeptidase 9) and ADAM10 (A Disintegrin and Metalloproteinase 10) with IC50s of 2.5 and 5.3 nM, respectively.

FT011 is a novel potent anti-inflammatory and anti-fibrotic agent that has been reported to attenuate organ damage in diabetic rats with cardiomyopathy and nephropathy. n diabetic rats, FT011 reduced retinal leukostasis, microglial density and mRNA levels of intercellular adhesion molecule-1 (ICAM-1).

Incyclinide (formerly known as CMT-3 and COL-3; 6-demethyl, 6-deoxy, 4-dedimethylamino TC; a chemically modified tetracycline) is a matrix metalloproteinase (MMP) inhibitor, it acts by inducing extracellular matrix degradation, and inhibiting angiogenesis, tumor growth and invasion, and metastasis.

Morroniside is a novel and potent neuroprotectant.

S-methyl-KE-298 is an active metabolite of KE-298, which is an inhibitor of matrix metalloproteinase (MMP-1) production from rheumatoid arthritis (RA) synovial cells.

(-)-Epigallocatechin (also known as EGC; Epigallocatechin; L-Epigallocatechin) is a naturally occurring polyphenol and flavonoid extractied from green tea, which shows multiple bioactivity.

Cordycepin is a novel and potent purine nucleoside antimetabolite and antibiotic.

Apigenin-7-glucuronide is a novel and potent bioactive compound that inhibits Matrix Metalloproteinases (MMP).

Actinonin is a naturally occurring antibacterial agent isolated from Actinomyces with antibiotic and anti-tumor activity.

Edaravone (formerly known as Radicut; MCI-186; NCI-C03952; NSC 12; Norantipyrine; Norphenazone; trade name: Radicava) is a novel and potent free radical scavenger that has been used clinically to reduce the neuronal damage following ischemic stroke.