S-methyl-KE-298
This product is for research use only, not for human use. We do not sell to patients.
For small sizes, please check our retail website as below: www.invivochem.com
| Size | Price | Stock |
|---|---|---|
| 100mg | $1600 | Check With Us |
| 250mg | $2400 | Check With Us |
| 500mg | $3600 | Check With Us |
: Cat #: V32859 CAS #: 143584-75-2 Purity ≥ 99%
Description: S-methyl-KE-298 is an active metabolite of KE-298, which is an inhibitor of matrix metalloproteinase (MMP-1) production from rheumatoid arthritis (RA) synovial cells.
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- Physicochemical and Storage Information
- Protocol
- Related Biological Data
- Stock Solution Preparation
- Quality Control Documentation
| Molecular Weight (MW) | 252.33 |
|---|---|
| Molecular Formula | C13H16O3S |
| CAS No. | 143584-75-2 |
| Synonyms | S-methyl-KE-298; S-methyl-KE298 |
| Protocol | In Vitro | S-methyl-KE-298 is a methyl conjugate of deacetyl-KE-298 is plasma. |
|---|
These protocols are for reference only. InvivoChem does not
independently validate these methods.
| Solvent volume to be added | Mass (the weight of a compound) | |||
|---|---|---|---|---|
| Mother liquor concentration | 1mg | 5mg | 10mg | 20mg |
| 1mM | 3.9631 mL | 19.8153 mL | 39.6306 mL | 79.2613 mL |
| 5mM | 0.7926 mL | 3.9631 mL | 7.9261 mL | 15.8523 mL |
| 10mM | 0.3963 mL | 1.9815 mL | 3.9631 mL | 7.9261 mL |
| 20mM | 0.1982 mL | 0.9908 mL | 1.9815 mL | 3.9631 mL |
The molarity calculator equation
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The dilution calculator equation
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This equation is commonly abbreviated as: C1 V1 = C2 V2
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Step One: Enter information below
Dosage mg/kg
Average weight of animals g
Dosing volume per animal µL
Number of animals
Step Two: Enter the in vivo formulation
%DMSO
+
%
+
%Tween 80
+
%ddH2O
Calculation Results:
Working concentration:
mg/ml;
Method for preparing DMSO master liquid:
mg
drug pre-dissolved in
µL
DMSO(Master liquid concentration
mg/mL)
,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation:
Take
µL
DMSO master liquid, next add
µL
PEG300, mix and clarify, next add
µL
Tween 80,mix and clarify, next add
µL
ddH2O,mix and clarify.
Note:
- (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
- (2) Be sure to add the solvent(s) in order.