Inosine pranobex (Imunovir; Delimmun; Groprinosin), a combinatinon of inosine, acetamidobenzoic acid, and dimethylaminoisopropanol, is a novel, potent, broad-spectrum antiviral agent potentially useful for HIV/AIDs infection.
Nelfinavir (formerly AG-1341) is a novel, potent and orally bioavailable HIV-1 protease inhibitor/PI with a Ki of 2 nM.
Emtricitabine S-oxide (also called Emtricitabine Degradant-III; Emtricitabine sulfoxide) is a degradation product (S-oxidized impurity) of Emtricitabine (BW-1592; FTC; BW1592; Emtriva; Coviracil; Racivir), which is a potent nucleoside reverse transcriptase inhibitor (NRTI) that has been approved for the treatment of both human immunodeficiency virus (HIV) and hepatitis B virus.
PF-3450074 (also known as PF74) is a HIV-1 capsid-targeting small molecule antiviral compound which directly binds to the capsid (CA) protein at a site also utilized by host cell proteins CPSF6 and NUP153. The RNA genome of human immunodeficiency virus type 1 (HIV-1) is enclosed in a cone-shaped capsid shell that disassembles following cell entry […]
Gardiquimod DiTFA salt is a specific TLR7 agonist with anticancer and anti-HIV-1 activities.
Indinavir (IDV; formerly DRG-0233; MK639 and L-735524; Crixivan) is an inhibitor of HIV protease approved for use as a component of highly active antiretroviral therapy to treat HIV/AIDS.
Indinavir sulfate (IDV; formerly known as MK-639; DRG-0233; L735524; trade name Crixivan), the sulfate salt of indinavir, is a potent and specific HIV protease inhibitor with antiviral effects and good oral bioavailability.
Bictegravir (formerly BIC; GS-9883; trade name: Biktarvy for the combination of bictegravir, embitcitabine, tenofovir alafenamide) is a novel, potent, once-daily, unboosted inhibitor of HIV-1 integrase (IN) approved in 2018 for HIV treatment.
Enfuvirtide, a peptide-based anti-HIV-1 fusion inhibitor, is an approved antiviral medication that prevents human immunodeficiency virus (HIV) from infecting healthy cells in the body.
Ro 24-7429 (Ro247429; Ro-247429) is a novel and potent Tat ( HIV-1 transactivator protein) antagonist with anti-HIV, antifibrotic and anti-inflammatory activities.