Amphotericin B methyl ester, the methyl ester derivative of Amphotericin B (A-634250), is a cholesterol-binding compound with potent antifungal activity.

Islatravir (formerly known as MK-8591; 4′-ethynyl-2-fluoro-2′-deoxyadenosine; EFdA; ISL) is a novel and potent anti-HIV-1 agent which acts as an NRTTI (nucleoside reverse transcriptase inhibitor) with anti-HIV activities.

Bevirimat (formerly known as PA-457, MPC-4326 and YK FH312), an analog of betulinic acid, is a novel and potent anti-HIV drug that acts as a maturation inhibitor. Existing antiretroviral treatments for HIV type-1 (HIV-1) disease are limited by problems of resistance and drug-drug interactions. Bevirimat has a mechanism of action that is distinct from other […]

BMS-378806 (also known as BMS 806) is a novel, potent, orally bioavailable small molecule that selectively inhibits the binding of HIV-1 gp120 to the CD4 receptor with EC50 of 0.85-26.5 nM in HIV virus. BMS-378806 inhibits the first step of HIV-1 infection by blocking the binding of host cell CD4 with viral gp120 protein. It […]

Saquinavir mesylate (Ro-31-8959; Invirase; Fortovase),an HIV Protease Inhibitor, is an antiretroviral drug used together with other medications to treat or prevent HIV/AIDS.

Fostemsavir Tris (BMS-663068 trisaminomethane or tromethamine or THAM) is the trisaminomethane salt of Fostemsavir (BMS663068; BMS-663068; Rukobia) which is an anti-HIV medication marketed in 2020.

Elsulfavirine is a novel and potent antiviral drug candidate.

3-Phenanthrenebutyric acid,also known as HIV-1 Nef-IN-1 or NSC-92828 , is a HIV-1 Nef protein inhibitor.