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Saquinavir mesylate (Ro 31-8959; Invirase; Fortovase)

This product is for research use only, not for human use. We do not sell to patients.

Saquinavir mesylate (Ro 31-8959; Invirase; Fortovase)
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
500mg$500Check With Us
1g$800Check With Us
5g$2025Check With Us

Cat #: V14330 CAS #: 149845-06-7 Purity ≥ 98%

Description: Saquinavir mesylate (Ro-31-8959; Invirase; Fortovase),an HIV Protease Inhibitor, is an antiretroviral drug used together with other medications to treat or prevent HIV/AIDS.

References: Kaldor et al (1995) Isophthalic acid derivatives: amino acid surrogates for the inhibition of HIV-1 protease. Bioorg.Med.Chem.Lett. 5 721.

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Product Promise

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Molecular Weight (MW)766.95
Molecular FormulaC39H54N6O8S
CAS No.149845-06-7
SMILES CodeO=C(N[C@@H](CC1=CC=CC=C1)[C@H](O)CN2C[C@@]3([H])CCCC[C@@]3([H])C[C@H]2C(NC(C)(C)C)=O)[C@@H](NC(C4=NC5=CC=CC=C5C=C4)=O)CC(N)=O 
SynonymsSaquinavir; brand names Invirase and Fortovase; Ro 31-8959; Ro 31-8959/000; Ro 318959; Sch 52852; Sch-52852; Sch52852;
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM1.3039 mL6.5193 mL13.0387 mL26.0773 mL
5mM0.2608 mL1.3039 mL2.6077 mL5.2155 mL
10mM0.1304 mL0.6519 mL1.3039 mL2.6077 mL
20mM0.0652 mL0.3260 mL0.6519 mL1.3039 mL
Quality Control Documentation
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
=
Concentration
×
Volume
×
Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
×
Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.