Datelliptium chloride, a ellipticine derivative, is a novel and potent DNA-intercalating agent with anti-cancer activities.
Cyclocytidine (formerly NSC-145668; Cyclo-C; NSC145668; Ancitabine) is a pyrimidine nucleoside-based prodrug of cytarabine that has to be activated through hydrolysis to cytarabine under in vivo conditions.
Sorivudine (BV-araU; Bravavir; ARYS-01; SQ-32756; BVAU; JA-001; YN-72; DRU-0136) is a novel and potent DNA polymerase inhibitor with the potential to be used for the treatment of herpes zoster (shingles).
Darusentan (formerly LU-135252 or HMR-4005) is an endothelin receptor antagonist (ERA)/inhibitor.
LMI-070 (Branaplam; NVS-SM1) is a potent, orally bioactive, small-molecule enhancer of SMN2 (survival of motor neuron-2) splicing that elevates full-length SMN protein and extends survival in a severe SMA mouse model.
Mechlorethamine HCl (chloramin; chlorethamine; mustine, HN2, Mustargen; and embikhin), the hydrochloride salt of Mechlorethamine, is the prototype of a class of anticancer chemotherapeutic drugs called DNA alkylators or DNA alkylating agents.
Plitidepsin (dehydrodemnin B; aplidine; Aplidin) is a naturally occurring cyclic depsipeptide extracted from the marine tunicate Aplidium albicans with a broad spectrum of anticancer activities.
Alovudine (MIV310; CL-184824; 3′-Fluoro-3′-deoxythymidine) is a novel and potent reverse transcriptase inhibitor (RTI) with the potential for the treatment of HIV infection.
Neobavaisoflavone is a naturally occurring flavonoid isolated from the seeds of Psoralea corylifolia with anti-inflammatory, anti-cancer and anti-oxidation activities.
Branaplam HCl (LMI-070 HCl; NVS-SM1) is a potent, orally bioactive, small-molecule enhancer of SMN2 (survival of motor neuron-2) splicing that elevates full-length SMN protein and extends survival in a severe SMA mouse model.