Neobavaisoflavone

This product is for research use only, not for human use. We do not sell to patients.

Neobavaisoflavone
For small sizes, please check our retail website as below: www.invivochem.com
Size Price Stock
100mg$330To Be Confirmed
500mg$550To Be Confirmed
1g$825To Be Confirmed

Cat #: V14759 CAS #: 41060-15-5 Purity ≥ 99%

Description: Neobavaisoflavone is a naturally occurring flavonoid isolated from the seeds of Psoralea corylifolia with anti-inflammatory, anti-cancer and anti-oxidation activities.

References: Chen H, et, al. Neobavaisoflavone inhibits osteoclastogenesis through blocking RANKL signalling-mediated TRAF6 and c-Src recruitment and NF-κB, MAPK and Akt pathways. J Cell Mol Med. 2020 Aug;24(16):9067-9084.

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Molecular Weight (MW)322.35
Molecular FormulaC20H18O4
CAS No.41060-15-5
ProtocolIn VivoNeobavaisoflavone (30 mg/kg; i.p. for 6 weeks) inhibits osteoclastogenesis, promotes osteogenesis and ameliorates bone loss in ovariectomized mice
Animal modelC57BL/6 female mice (8 weeksd; 20-25 g) were removed bilateral ovaries
Dosages30 mg/kg
AdministrationI.p. for 6 weeks
These protocols are for reference only. InvivoChem does not independently validate these methods.
Preparing Stock Solutions
Solvent volume to be added Mass (the weight of a compound)
Mother liquor concentration 1mg5mg10mg20mg
1mM3.1022 mL15.5111 mL31.0222 mL62.0444 mL
5mM0.6204 mL3.1022 mL6.2044 mL12.4089 mL
10mM0.3102 mL1.5511 mL3.1022 mL6.2044 mL
20mM0.1551 mL0.7756 mL1.5511 mL3.1022 mL
The molarity calculator equation
Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)
Mass
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Concentration
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Volume
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Molecular Weight*
The dilution calculator equation
Concentration(start) × Volume(start) = Concentration(final) × Volume(final)

This equation is commonly abbreviated as: C1 V1 = C2 V2

Concentration(start)
C1
×
Volume(start)
V1
=
Concentration(final)
C2
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Volume(final)
V2
Step One: Enter information below
Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals
Step Two: Enter the in vivo formulation
%DMSO + % + %Tween 80 + %ddH2O

Calculation Results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.
Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH2O,mix and clarify.
Note:
  • (1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
  • (2) Be sure to add the solvent(s) in order.