Adenine HCl (6-Aminopurine; Vitamin B4; NSC 14666; NSC-14666), the hydrochloride salt of adenine, is a purine analog and an adenine receptor agonist with a Ki of 18 nM at rat adenine receptors.
Bleomycin Sulfate (also known as NSC125066; NSC-125066; BLEO-cell; Bleolem; Blenoxane; Blanoxan), the sulfate salt of Bleomycin, is a glycopeptide antibiotic and an anticancer agent approved for treating a variety of cancers including Hodgkin’s lymphoma, non-Hodgkin’s lymphoma, ovarian cancer, testicular cancer, and cervical cancer.
Ifosfamide (formerly NSC-109724, Isophosphamide; Ifomide; Iphosphamid; iphosphamide; Isoendoxan; IsoEndoxan; Naxamide; Cyfos; Ifex; Ifosfamidum) is an approved anticancer medication which acts as a nitrogen mustard and DNA alkylating agent/alkylator.
Remdesivir (GS-5734; Veklury) is an FDA approved drug for the treatment of 2019-nCoV (COVID-19 pandemic, CoronaVirus) infections requiring hospitalization.
Nimustine hydrochloride (also known as ACNU), an approved chemotherapeutic drug, is a potent DNA cross-linking and DNA alkylating agent for cancer treatment, it induces DNA replication blocking lesions and DNA double-strand breaks and inhibits DNA synthesis, commonly used in chemotherapy for especially glioblastomas / malignant brain tumors.
Nelarabine (formerly 506 U78; GW-506U78; NS-686673; 506U78, GW506U78; Atriance; Arranon; Nelzarabine) is a cytotoxic/chemotherapeutic medication approved for use in the treatment of hematological malignancies (T-cell acute lymphoblastic leukemia and T-cell lymphoblastic lymphoma).
Mirin is a potent inhibitor of the MRN (Mre11 / Rad50 / Nbs1) complex and Ataxia Telangiectasia-Mutated (ATM) protein kinase.
Cladribine (also known as 2-CdA, 2-chlorodeoxyadenosine; Leustatin; Leustat; Leustatine), a purine nucleoside antimetabolite analogue and an approved medication used for treating hairy cell leukemia and B-cell chronic lymphocytic leukemia, is an adenosine deaminase inhibitor for U266, RPMI8226, and MM1.S cells with IC50s of approximately 2.43 μM, 0.75 μM, and 0.18 μM, respectively.
Carmustine (Nitrumon; NSC 409962), an DNA crosslinking and alkylating nitrosourea, is a potent antitumor chemotherapeutic agent.
Enoxacin (also known as AT-2266, CI919, Pd107779, NSC 629661) is an orally bioavailable, broad-spectrum antibacterial agent of the fluoroquinolone class.