Cytarabine (formerly Ara-C; MK-8242; SCH-900242; SCH900242; MK8242; AC-1075; CHX 3311; Arabitin; Aracytidine), a pyrimidine nucleoside analog approved for cancer treatment, is an antimetabolite anticancer drug used mainly for treating leukemia.
RG3039 (also known as PF-06687859; PF 06687859), a member of a chemical series that was identified and optimized using an SMN2 promoter screen, is a novel, potent, orally bioavailable and brain-penetrant DcpS (decapping scavenger enzyme) inhibitor with an IC50 of 0.069 nM.
Mizoribine (also called Bredinin, HE-69; He69; NSC289637; NSC-289637) is an imidazole-based nucleoside isolated from the fungus Penicillium brefeldianum.
NKP-1339 (IT139; KP1339) is the first-in-class and potent ruthenium-based anticancer drug under clinical investigation for treating solid cancer with limited side effects.
Daphnetin (NSC-633563; NSC633563; 7,8-dihydroxycoumarin), a naturally occuring coumarin analog isolated from plants of the genus Daphne, is a PKI-protein kinase inhibitor with important biological activity (e.g. anti-inflammatory and anti-oxidant effects).
BCH001 is a novel and specific PAPD5 inhibitor and it is used to regulate aging.
Thymidine (also known as deoxythymidine; other names deoxyribosylthymine, thymine deoxyriboside) is a pyrimidine deoxynucleoside used as a cell synchronizing agent.
Filibuvir (PF00868554; PF-00868554) is a novel and potent NS5B inhibitor of the non-nucleoside inhibitor (NNI) class developed for the treatment of hepatitis C.
Carboplatin (formerly known as JM-8, CBDCA, NSC-241240; Paraplat; Paraplatin; Blastocarb; Carboplat; Carbosin; Carbosol; Carbotec; Displata; Ercar) is an approved anticancer drug that acts as a DNA synthesis inhibitor by binding to DNA (DNA alkylator) and interfering with the cell’s repair mechanism in cancer cells.
RG7800 (also known as RG-7800; RO6885247) is a potent and selective survival motor neuron 2 (SMN2) splicing modifier, which is currently being studies in human clinical trials for the treatment of Spinal Muscular Atrophy (SMA).