Aztreonam (also known as SQ 26776) is a synthetic monocyclic beta-lactam antibiotic, used to treat Gram-negative aerobic bacteria infection. It has a very high affinity for penicillin-binding protein 3 (PBP-3). Aztreonam causes significant suppression of human colony forming unit-erythroid (cfu-e), burst forming unit-erythroid (bfu-e) and colony forming unit-granulocyte macrophage (cfu-gm) at both peak and trough […]

Sutezolid (also known as U-100480; U-480; PF-2341272; PNU-100480; PNU-480) is a novel, potent oxazolidinone antimicrobial agent being developed for the treatment of tuberculosis, especially drug-resistant tuberculosis.

Cethromycin (also known as ABT-773, Abbott-195773, A-195773) is a ketolide antibiotic with a similar mechanism of action to telithromycin with an apparently better safety profile.

Triclocarban (3,4,4′-Trichlorocarbanilide) is an antimicrobial / antibacterial compound that is widely used in personal cleaning / personal care products.

Narirutin is a novel and potent anti-inflammatory agent, antidepressant agent.

Fosfomycin calcium (MK-0955 calcium) is a potent, blood-brain barrier penetrant phosphoenolpyruvate analog produced by Streptomyces and a synthetic broad-spectrum antibiotic with antimicrobial and bactericidal properties.

Omadacycline HCl (PTK-0796; trade name: Nuzyra), the hydrochloride salt of omadacycline, is an aminomethyl tetracycline antibiotic approved in 2018 to treat community-acquired bacterial infections such as acute bacterial skin and skin structure infections (ABSSSI), community-acquired bacterial pneumonia (CABP), and urinary tract infections (UTI).

Deprodone propionate (RD-20000; RD 20000; RD20000) is a corticosteroid used as a topical antiinflammatory agent.

Pretomanid (also known as PA-824; PA824), a bicyclic nitroimidazolepyran analog, is a novel, potent and selective anti-tuberculosis (TB) drug approved in 2019 for treating multi-drug-resistant tuberculosis with an MIC of less than 2.8 μM. It is generally used together with bedaquiline and linezolid. PA-824 has been found to exhibit bactericidal activity against replicating bacilli and […]

Azomycin (2-Nitroimidazole) is an antimicrobial antibiotic extracted from a strain of Nocardia mesenterica and an unidentified Streptomyces. Azomycin is active against aerobic Gram-positive and Gram-negative bacteria. The structure of azomycinis a 2-nitroimidazole. Reduction of azomycin abolish the bacteriostatic activities. Also the closely related analog, 4-nitroimidazole does not exhibit bacteriostatic effects.