Amikacin is an aminoglycoside antibiotic used for a number of bacterial infections including joint infections, intra-abdominal infections, meningitis, pneumonia, sepsis, and urinary tract infections. It is also used for the treatment of multidrug-resistant tuberculosis. It is used either by injection into a vein or muscle. Amikacin, like other aminoglycoside antibiotics, can cause hearing loss, balance […]

Delafloxacin MEGLUMINE (WQ-3034; ABT-492; RX-3341; WQ3034; ABT492; RX3341; Baxdela), the MEGLUMINE salt of Delafloxacin, is an antibiotic of the quinolone class approved in 2017 by FDA to treat patients with acute bacterial skin infections.

Enmetazobactam (AAI101) is a novel potent and extended-spectrum beta lactamase inhibitor with the potential to be used for the treatment of multi-drug resistant gram-negative bacterial infections.

Demeclocycline HCl (also known as demeclocycline hydrochloride; trade names: Detravis; Ledermycin), a protein translation inhibitor and potential calpain inhibitor, is a potent tetracycline antibiotic that inhibits the protein synthesis in bacteria, it is used for the treatment of bacterial infections. Demeclocycline is a semisynthetic tetracycline antibiotic which was derived from a strain of Streptomyces aureofaciens. […]

Kanamycin sulfate, the sulfate salt of Kanamycin (Kanamycin A; Kantrex; Kanamycine), is an aminoglycoside bacteriocidal antibiotic effective against gram-positive and negative bacteria and mycoplasma.

Garenoxacin (formerly BMS284756; T-3811ME, BMS-284756; tradename: Geninax) is a newly developed and orally bioavailable quinolone-based antibiotic for the treatment of Gram-positive and Gram-negative bacterial infections. Measurement of the MIC and the mutant prevention concentration (MPC) revealed that garenoxacin was 20-fold more potent than ciprofloxacin for a variety of ciprofloxacin-susceptible isolates, some of which were resistant […]

Omadacycline (PTK-0796; PTK0796; trade name: Nuzyra) is a novel, aminomethyl tetracycline antibiotic being developed and was approved later in 2018 for oral and intravenous (IV) administration to treat community-acquired bacterial infections such as acute bacterial skin and skin structure infections (ABSSSI), community-acquired bacterial pneumonia (CABP), and urinary tract infections (UTI). In Oct 2018, Omadacycline was […]

Faropenem medoxomil (Faropenem daloxate; Faropenem medoxil) is an orally bioactive beta-lactam antibiotic of the penem class.

Levo-Ornidazole [also known as (S)-Ornidazole; Levornidazole] is the levo-isomer of ornidazole which is a 5-nitroimidazole derivative with antiprotozoal and antibacterial properties against anaerobic bacteria. Levo-Ornidazole is the less active isomer. Ornidazole is a approved drug that cures some protozoan infections. It has been investigated for use in Crohn’s disease after bowel resection. Synthesis is a […]

Ertapenem (L-749345; Invanoz; MK-0826; Invanz) is a 1-β-methyl carbapenem antibiotic marketed by Merck as Invanz. Ertapenem is a long-acting, broad-spectrum antibiotic of β-lactam subclass. Ertapenem has a broad spectrum of antibacterial activity including common aerobic and anaerobic bacteria and organisms with extended-spectrum β-lactamases. Ertapenem is an inhibitor of bacteria cell-wall synthesis, it acts by binding […]