Amikacin | CAS 39831-55-5

Amikacin

This product is for research use only, not for human use. We do not sell to patients.

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Size	Price	Stock
10g	$250	Check With Us
25g	$400	Check With Us
50g	$600	Check With Us

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Cat #: V3548 CAS #: 39831-55-5 Purity ≥ 98%

Description: Amikacin is an aminoglycoside antibiotic used for a number of bacterial infections including joint infections, intra-abdominal infections, meningitis, pneumonia, sepsis, and urinary tract infections. It is also used for the treatment of multidrug-resistant tuberculosis. It is used either by injection into a vein or muscle. Amikacin, like other aminoglycoside antibiotics, can cause hearing loss, balance problems, and kidney problems. Other side effects include paralysis, resulting in the inability to breathe. If used during pregnancy it may cause permanent deafness in the baby. Amikacin works by blocking the function of the bacteria's 30S ribosomal subunit, making it unable to produce proteins.

References: Edson, R.S. and C.L. Terrell, The aminoglycosides. Mayo Clin Proc, 1999. 74(5): p. 519-28.

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Physicochemical and Storage Information
Protocol
Related Biological Data
Stock Solution Preparation
Quality Control Documentation

Molecular Weight (MW)	781.752
Molecular Formula	C22H47N5O21S2
CAS No.	39831-55-5
Storage	-20℃ for 3 years in powder formr
Storage	-80℃ for 2 years in solvent
SMILES Code	NCC[C@@H](C(N[C@@H]1C[C@@H]([C@H]([C@@H]([C@H]1O[C@H]2O[C@@H]([C@H]([C@@H]([C@H]2O)N)O)CO)O)O[C@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)CN)N)=O)O.OS(=O)(O)=O.OS(=O)(O)=O
Synonyms	AY-416651 sulfate; BAY416651 sulfate; BAY416651 sulfate; Amikacin sulfate; Amitrex; Antibiotic BB-K8 sulfate; BB-K8; Biklin; Biodacyn; Chemacin; Fabianol; Kaminax; Kancin-Gap; Likacin; Lukadin; BB K8; BBK8

Preparing Stock Solutions

Solvent volume to be added	Mass (the weight of a compound)
Mother liquor concentration	1mg	5mg	10mg	20mg
1mM	1.2792 mL	6.3959 mL	12.7918 mL	25.5836 mL
5mM	0.2558 mL	1.2792 mL	2.5584 mL	5.1167 mL
10mM	0.1279 mL	0.6396 mL	1.2792 mL	2.5584 mL
20mM	0.0640 mL	0.3198 mL	0.6396 mL	1.2792 mL

Quality Control Documentation	Select Batch Purity ≥ 98% COA MSDS NMR HPLC

The molarity calculator equation

Mass(g) = Concentration(mol/L) × Volume(L) × Molecular Weight(g/mol)

Mass

Concentration

Volume

Molecular Weight*

The dilution calculator equation

Concentration_(start) × Volume_(start) = Concentration_(final) × Volume_(final)

This equation is commonly abbreviated as: C₁ V₁ = C₂ V₂

Concentration_(start)

Volume_(start)

Concentration_(final)

Volume_(final)

Step One: Enter information below

Dosage mg/kg Average weight of animals g Dosing volume per animal µL Number of animals

Step Two: Enter the in vivo formulation

%DMSO + % + %Tween 80 + %ddH₂O

Calculation Results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in µL DMSO(Master liquid concentration mg/mL) ,Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation: Take µL DMSO master liquid, next add µL PEG300, mix and clarify, next add µL Tween 80,mix and clarify, next add µL ddH₂O,mix and clarify.

Note:

(1) Please be sure that the solution is clear before the addition of next solvent. Dissolution methods like vortex, ultrasound or warming and heat may be used to aid dissolving.
(2) Be sure to add the solvent(s) in order.